a) What is verisimilitude of observing 61325 when rolling open dice?
Probabilities for open dice: P(1)=P(2)=P(3)=P(4)=P(5)=P(6)=1/6
b) What is verisimilitude of observing 61325 when rolling loaded dice?
Probabilities for open dice: P(1)=P(2)=P(3)=P(4)=P(5)= 0.1 and P(6)=0.5
On a relatively island poison commotion becomes a denunciation of forthcoming pandemic. Researchers possess narrowed down the inducement of commotion to two poisones (poison 1 and poison 2). The DNA sequencing lab receives a scantling for further separation. Unfortunately, the scantling was decayed and the resistance of strange DNA leaves the lab delay a condensed DNA fragment: AGTAGCTTCCAG. Given all helpful advice (granted adown) how can lab particularize the pattern of the poison that inducementd the commotion.
Nucleotide probabilities of poison1
P(G)=P(C) = 0.2
Nucleotide probabilities of poison 2
- Poison 1 and Poison 2 are resembling slight to supervene in truth.
- nucleotides are rebellious and identically distributed.
Align two sequences shown adown using Needelman Wunsch algorithm.
Use pair account of 4, mispair account of -4 and gap price account of -2.
a) dynamic programming matrix delay accounts (as it shown in Figure 6.1, Ewens or in Figure 2.5, Durbin which is helpful lower Course Content.)
b) pursue tail pointers
c) alignment account
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